MyBioSource.com's TPX2 Antibody is a Mouse monoclonal antibody. It reacts with Human. This antibody has been shown to work in applications such as: ELISA, and Western Blot.
Description
Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation